The Pryer lens is a new endoscopic objective compatible with common optical microscopes, especially modern Two-photon microscopes. An unconventional optical design combines a very small tip size to be minimally invasive with a large numerical aperture for high resolution.
This state-of-the-art objective allows for in vivo deep tissue access and visualization in difficult-to-reach regions such as the hippocampus. Image acquisition with subcellular spatial resolution at sub-second sampling rates becomes a reality.
The Pryer lens is a combined endoscopic objective and is compatible with any fluorescence microscopes, such as current Two-photon microscopes from Olympus and Nikon. This state-of-the-art objective allows for deep tissue access and visualization in anesthetized animals, awake animals with head fixation, and even chronic recordings.
It is composed of 7 lenses within its unique slim tip which makes it suitable for minimally invasive endoscopic imaging applications.
|Type||Plan Fluorite NIR|
|Correction||Infinity / Zero cover glass thickness|
|Tip diameter||2.1 mm|
|Field of view||200µm|
The Pryer lens is compatible with all major types of objective mounts.
In vivo image recording from mouse hippocampus with the Pryer endoscopic objective
In vivo image recording from deep layers in mouse cortex with the Pryer endoscopic objective
A collection of z-stacks and 3D representations recorded with the Pryer lens is available here: Pryer_Lens_Video Examples