The optomotor response measurement (OMR) is a proven method to assess visual function in rodents. The PhenoSys qOMR-XT extends the qOMR product line to applications where larger animals, such as adult rats are to be studied. It is a unique system that objectively measures the OMR with minimal experimenter effort. Based on real-time head tracking, quantitative OMR measurements automatically provide visual acuity and contrast sensitivity. This is a PhenoSys Collaboration product brought to market together with its developer, Dr. Friedrich Kretschmer.
General application areas:
Characterisation or preclinical testing in relevant disease models, for example:
Investigation of various aspects of vision in mice and other rodents:
qOMR-XT with opened lid
qOMR-XT with wheeled stand
qOMR-XT with rat on pedestal
Francia S, Shmal D, Di Marco S, Chiaravalli G, Maya-Vetencourt JF, Mantero G, Michetti C, Cupini S, Manfredi G, DiFrancesco ML, Rocchi A, Perotto S, Attanasio M, Sacco R, Bisti S, Mete M, Pertile G, Lanzani G, Colombo E, Benfenati F. Light-induced charge generation in polymeric nanoparticles restores vision in advanced-stage retinitis pigmentosa rats. Nat Commun. 2022 Jun 27;13(1):3677. doi: 10.1038/s41467-022-31368-3. PMID: 35760799; PMCID: PMC9237035.