The optomotor response (OMR) is a reflex used to assess visual function. To evoke OMR, a mouse watches a striped pattern rotating within a cylinder. Stimulus-correlated head movements are quantified to determine visual thresholds.
The PhenoSys qOMR (quantitative OMR) is a unique system that automatically measures the OMR with minimal experimenter effort. It uses a virtual stimulation cylinder that continuously aligns with the animal´s head position. Based on real-time head tracking, quantitative OMR measurements run fully automatically and objectively. This is a PhenoSys Collaboration product that is brought to market together with its developer, Dr. Friedrich Kretschmer.
2. Characterisation or preclinical testing in relevant disease models, for example:
3. Examination of axonal regeneration.
The PhenoSys qOMR is a PhenoSys Collaboration product. These products are brought to market together with the scientists who developed them.
qOMR is a joint product of Dr. Friedrich Kretschmer and PhenoSys.
qOMR is based on his publications:
Principle of the experiment with a mouse on top of the platform. The stimulus is normally invisible to the IR camera.
Video-based real-time tracking of head movement.
Software omrStudio: stimulus design.
Software omrStudio: running experiment.
Actual measurement data (single frame) and recorded video with superimposed tracking results:
qOMR video with visible stimulus.
The visibility of the stimulus is enhanced compared to the normal qOMR for better clarity.
Software omrStudio: data analysis.