Lasztoczi and Klausberger. Layer-Specific GABAergic Control of Distinct Gamma Oscillations in the CA1 Hippocampus.

The original formulation of Gate Control Theory (GCT) proposed that the perception of pain produced by spinal cord signaling to the brain depends on a balance of activity generated in large (nonnociceptive)- and small (nociceptive)-diameter primary afferent fibers. The theory proposed that activation of the large-diameter afferent “closes” the gate by engaging a superficial dorsal […]