Large-scale two-photon calcium imaging in freely moving mice.

Body weight is maintained through homeostatic mechanisms that balance energy intake and energy expenditure. To combat obesity, research has focused on activating thermogenesis, which accounts for 10%–15% of daily energy expenditure in humans but can expand to 30% with maximal activation (Ouellet et al., 2012). Adipocytes are central players in body weight maintenance and thermogenesis. There […]