Spatially heterogeneous acetylcholine dynamics in the striatum promote behavioral flexibility
Being able to switch from established choices to new alternatives when conditions change – behavioral flexibility – is essential for survival. Cholinergic signaling in the striatum contributes to such flexible behavior, yet…
Johann, K., et al. Thyroid-hormone-induced browning of white adipose tissue does not contribute to thermogenesis…
Neurons in prefrontal cortex (PF) represent mnemonic information about current goals until the action can be selected and executed. However, the neuronal dynamics underlying the transition from goal into specific actions are…
Martire, V. L., et al. The physiological signature of daily torpor is not orexin dependent.
Under conditions of scarce food availability and cool ambient temperature, the mouse (Mus Musculus) enters into torpor, a state of transient metabolic suppression mediated in part by the autonomic nervous system. Hypothalamic…
Oelkrug, R., et al. Maternal Brown Fat Thermogenesis Programs Glucose Tolerance in the Male Offspring.
Environmental temperature is a driving factor in evolution, and it is commonly assumed that metabolic adaptations to cold climates are the result of transgenerational selection. Here, we show in mice that even…
Yamagata, T., et al. The hypothalamic link between arousal and sleep homeostasis in mice.
Sleep and wakefulness are not simple, homogenous all-or-none states but represent a spectrum of substates, distinguished by behavior, levels of arousal, and brain activity at the local and global levels. Until now,…
Wellbrock, A. H. J., et al. Cool birds: first evidence of energy-saving nocturnal torpor in free-living commonswifts Apus apus resting in their nests.
Daily torpor is a means of saving energy by controlled lowering of the metabolic rate (MR) during resting, usually coupled with a decrease in body temperature. We studied nocturnal daily torpor under…