Metabolic Monitoring: Indirect Calorimetry

Advanced push-button system for automated measurement of metabolic rate, energy expenditure, respiratory exchange and more in mice, rats, and birds.

What we offer

Automated Metabolic Analysis

Automated measurement and calculation of key metabolic parameters (metabolic rate, energy expenditure, respiratory exchange ratio).

Comprehensive Data

Precise analysis of O2 consumption, CO2 production, and water vapor evaporation.

Precise Mesaurement

Reliable data for understanding animal metabolism, nutrition, thermoregulation, activity, and energy balance.

One Size Fits Many

Solutions for small animals including mice, rats, and birds.

Challenges we address

Complexity and High entry Barrier

The CaloBox revolutionizes indirect calorimetry with its ‘Push-Button’ design making these measurements feasible for every researcher.

Accuracy & Reliability

The automatic zero adjustment and direct measurement of water vapor ensures consistent and accurate data collection.

Data Access

Direct report of energy expenditure and respiratory exchange ratio, while also making all raw data accessible

The Core Technology Behind the Solution

High-precision, real-time metabolic gas quantification

Integrated humidity compensation – no drying of air required

Automated differential measurement & self-calibration

Direct calculation and reporting of key metabolic parameters

Tailored for Your Research: Calobox- Indirect Calorimetry System

The CaloBox is a fully automated system engineered for accurate indirect calorimetry measurements in small animals, including mice, rats, and birds. It is ideal for studies related to animal  metabolism, nutrition, thermoregulation, torpor, bio-energetics and behavior.

The  CaloBox is a PhenoSys Collaboration product. These products are brought to market together with the scientists who developed them. The CaloBox is a joint product of Prof. Dr. Gerhard Heldmaier and PhenoSys.

The CaloBox- Push Button Calorimetry

Set-up With Small Animal Cuvette & Laptop

Close-Up Results View

Close-Up View

Key Benefits

Automated Parameter Calculation

Automatically measures and calculates vital parameters such as metabolic rate, Energy Expenditure (EE), and Respiratory Exchange Ratio (RER).

Precise Gas Analysis

Measures O2, CO2, and water vapor content in sample air, comparing it to reference air for high accuracy.

Comprehensive Metabolic Data

Provides V′O2 (O2 consumption), V′CO2 (CO2 production), V′H2O (water vapor evaporation), and RER/RQ, alongside calculated Energy Expenditure (EE).

Automatic Sensor Adjustment

Features automated adjustment of gas sensors with reference air at pre-set intervals, ensuring data reliability.

Versatile Animal Compatibility

Suitable for a range of small animals including mice, rats, and birds.

User-Friendly Turnkey Setup

Packages intuitive plugs, sensor, pump, a display, and switches combined with Pre-installed software package and a tubing set in a compact format for straightforward operation.

Reliable for Long-Term Studies

Enables continuous, unattended monitoring for extended periods, ideal for studies related to animal metabolism, nutrition, thermoregulation, torpor, bio-energetics and behavior.

How it Works

The CaloBox operates by continuously sampling air from the animal’s chamber and analyzing its O2, CO2, and water
vapor content. By comparing this to a reference air , the system precisely determines gas exchange rates, allowing for the real-time calculation of metabolic parameters and energy expenditure, providing a comprehensive metabolic
profile.

Publications

We are committed to advancing scientific discovery through robust, validated solutions.

This section highlights peer-reviewed publications that showcase the diverse applications and impactful discoveries made possible by our technology, contributing to the broader scientific community’s knowledge base.

Got Questions? We're Just a Message Away

We recognize the unique requirements of every research endeavor. Our team is ready to connect and discuss your specific use case, exploring how our solutions fit o your project.

Our commitment extends far beyond consultation and sales. We become your dedicated partner, ensuring seamless integration with existing setups and providing comprehensive, ongoing support to help your research thrive.